Preparation of Amino-modified Silica Gel Using A Simple Sol-Gel Method

摘要：

Amino-modified silica gel (N-MSG) has been prepared by a simple sol-gel processing via the co-condensation of commercial silica sol with 3-aminopropyltrie-oxysilane (APTES). Penicillin G acylase, as a model enzyme, was covalently immobilized on to the N-MSG. The samples were characterized by the Nitrogen sorption analysis, scanning electron microscopy (SEM), FT-IR and thermal gravimetric analysis (TGA). The results show that the amino-modified gel is a mesoporous material with an average pore size 12.64 nm. The surface area and total pore volume of N-MSG are 129.6 m2/g and 0.404 cm3/g, respectively. The immobilization process is efficient and the immobilized enzyme shows high catalytic efficiency. This sol-gel preparation is simple and shows prominent potential value in industrial processes.

关键词： Mesoporous materials Covalent immobilization Penicillin G acylase Amino-modified silica gel

作者: Weibing Dong Junbo Gong Victor C. Yang

作者单位: Tianjin Key Laboratory for Modern Drug Delivery and High Efficiency, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 383-388

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）