The Preparation of Poly Ethylene Glycol Pellets by A New Vibrating Crusher Machine

摘要：

In this paper, a new vibrating crusher machine with the controlled system of liquid flow rate and the stirring device in coagulation line for avoiding the pellet conglutination was designed and used to prepare the pellets of poly ethylene glycol. The effect factors in average size and diameter deviation including the amplitude and frequency of the vibration and the flow rate of the liquid were discussed by response surface methodology and the Rayleigh theory. The mixing speed and power of stirring device were evaluated by calculating mixing power number. The experiments show that the equipment can be controlled conveniently and work stable and suitable for preparing pellets with Chinese and Western medicines.

关键词： pellets vibrating crusher machine stirring device response surface methodology Rayleigh theory

作者: Wang Kang He Mingxia Qing Li Liu Yanjun He Zhimin

作者单位: Enzyme Technology Laboratory, Chemical Engineering Research Center, School of Chemical Engineering a College of Precision Instrument and Opto-electronics Engineering, Tianjin University, Tianjin 300072

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 428

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）