SYNTHESIS AND CHARACTERIZATION OF WATER-DISPERSED TWO-PHOTON ABSORPTION NANOPARTICLE
Two-photon absorption (TPA) process is gaining increasing attention, wherein two photons are absorbed simultaneously. Quantum mechanically, a single photon excites the molecule to a virtual intermediate state, and the molecule is eventually brought to the final excited state by the absorption of the second photon. TPA has two key features, namely, the ability to create excited states with photons of half the nominal excitation energy, which can provide improved penetration in absorbing or scattering media, and a high degree of spatial selectivity in three dimensions. These features determine the potential application of TPA compounds in biological field, such as the two-photon photodynamic therapy for cancers3. However, most TPA compounds are hydrophobic with inherently poor water solubility and cannot be simply injected into biological system. Thus, Nanoparticles (Nps) fabricated by TPA materials dispersed in water have been reported, such as silica Nps4 and polymer Nps5. A challenge remaining to be solved in these methodologies is inevitable dilution of the active dye in a nanoparticle carrier, the loading amount of which is quite limited to a lower level. As a result, a new approach toward a water dispersion of dyeconcentrated Nps with large two-photon activity, by employing self-assembled nanoaggregates of active dye, was developed.
Shumin Yang Leilei Tian Dan Lu Yuguang Ma
Statel Key Laboratory for Supramolecular Structure and Materials,Jilin University,Changchun,China
国际会议
International Symposium on Polymer Physics(2008年国际高分子物理学术会议PP2008)
厦门
英文
270-271
2008-06-08（万方平台首次上网日期，不代表论文的发表时间）