POLYMERIC ADDITIVES CONTROL THE MORPHOLOGY OF LYSOZYME CRYSTAL

摘要：

X-ray crystallography is one of the most important research techniques to obtain the three-dimensional structure of protein single crystals. However, protein single crystals for X-ray crystallography test are difficult to be obtained in the proteinstructure determination process.1,2 The growth of protein single crystals is affected by many factors, including nature of protein, precipitants, temperature, additives and so on. Recently, additives affecting protein crystallization have been received more and more attention. For example, poly(ethylene glycol) (PEG) has been comprehensively used for screening crystallization conditions.3,4 But using polymeric additives to facilitate the process of protein crystallization is comparatively rare, and the mechanism is not very clear.5

作者: Juping Yang Jianjun Zhou Lin Li

作者单位: State Key Laboratory of Polymer Physics and Chemistry,Institute of Chemistry,Chinese Academy of Sciences,Beijing (100190),China

会议类型: 国际会议

会议名称: International Symposium on Polymer Physics(2008年国际高分子物理学术会议PP2008)

会议地点: 厦门

会议语种:英文

页码: 290-291

在线出版日期: 2008-06-08（万方平台首次上网日期，不代表论文的发表时间）