Effects of EMP irradiation on production of IL-2 in spleen cells of mice
AIM To investigate the bioeffects of EMP irradiation on the mouse immune system.METHODS EMP irradiation (field intensity: 57kV/m,300000 pulses, at free posture),Concentration of IL-2 in supematants of mouse spleen cells in groups of control and EMP irradiation was examined by ELISA.RESULTS Concentration ofIL-2 was 50.7+24.7 (P=0.285),169.6±63.9 (P< 0.01),52.2±12.4 (P=0.319),263.9-4-31.5(P<0.01) and 85.9±a:24.3 (pg/ml) in groups of 6h,24h,48h,96h after EMP irradiation and control respectively.IL-2 concentration in groups of 24h and 96h after EMP irradiation significantly increased (2 times and 3 times of control group respectively,P<0.01).While compared with that of control group,IL-2 concentration in groups of 6h and 48h after EMP irradiation decreased (about 40 percent,P<0.05).In phases,IL-2 concentration went down and up, then down and up again,just like a Cosine wave.CONCLUSION Results demonstrate that the production of IL-2 in spleen cells of mice fluctuates at different time after EMP irradiation under our experimental conditions.
EMP spleen cells IL-2 mice
Kangchu Li Guozhen Guo Shirong Ma Guiying Zeng Dongqing gen Junye Liu Jing Li Yurong Li Guirong Ding Yao Guo
国际会议
Asia-Pacific Conference on Environmental Electromagnetics CEEM2009(第五届亚太环境电磁学学术会议)
西安
英文
234-237
2009-09-16（万方平台首次上网日期，不代表论文的发表时间）