Estimation of Crystal Size Distribution Based on Photomicrograph
Crystal size distribution is important for the production of pharmaceuticals and many other products in a number of industries. A new method to estimate the crystal size distribution is developed based on crystal photomicrographs acquired from an optical microscope imaging system. The calibration of the imaging system is implemented by using a micrometer as a reference. Then particle size information is extracted from each of a set of crystal images through image processing techniques. Finally, according to the least square principle, different distribution functions are adopted to fit the particle size distribution respectively and the result with the minimum square error sum is chosen as the true size distribution. An industrial application shows that the proposed method can provide a satisfactory estimation for the particle size distribution.
Crystal size distribution Photomicrograph Calibration Image processing Curve fitting
Dongdong Wei Yuhong Zhao
Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, China
国际会议
2009年中国控制与决策会议(2009 Chinese Control and Decision Conference)
广西桂林
英文
1465-1470
2009-06-17（万方平台首次上网日期，不代表论文的发表时间）