An improved Position Weight Matriz method based on an Entropy Measure for the Recognition of Prokaryotic Promoters
In this paper, an improved position weight matrix (PWM) method is proposed based on an entropy measure for the recognition of prokaryotic promoters. In this method, the conservative sites of the prokaryotic promoters are firstly extracted according to an entropy measure, two improved position weight matrices are then constructed, after which by using the values of the matrix elements in the specific columns corresponding to the extracted conservative sites, the test sequences are scored and subsequently classified. Experiment results on several data sets show that the proposed algorithm outperforms the existing algorithms.
prokaryotic promoters information entropy position weight matriz (PWM)
Qinqin Wu Jiajun Wang Hong Yan
School of Electronics & Information Engineering Soochow University Suzhou,China Department of Electronic Engineering,City University of Hong Kong Kowloon,Hong Kong
国际会议
北京
英文
1-4
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）