Evolution of the major histocompatibility complez genes in fish
The major histocompatibility complex (MHC) is a gene cluster directly related to immune response and because of its important immunological functions, the structure and evolution history of MHC is of great interest to worlds scientists. To elucidate the evolutionary history of MHC, the MHC class Ⅱ antigen genes of 7 kinds of marine fish and 8 kinds of freshwater fish were selected. Then the phylogenetic relationships were explored by neighbour-joining and minimum-evolution methods. Based on two kinds of phylogenetic analysis, we knew that MHC evolutionary changes occurred in the early stage, but its followed by a period of evolutionary stability. The conclusion will provide guides for further research on MHC evolution history of other vertebrates.
MHC evolution phylogenetic tree fish
Xuemei Qiu Feng Zhang Xiangying Meng Yibing Zhou Xiuli Wang
Key Laboratory of Marine Bio-resourses sustainable utilization in Liaoning Provinces University,Dal Key Laboratory of Marine Bio-resourses sustainable utilization in Liaoning Provinces University,Dal
国际会议
北京
英文
1-4
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）