The influence of amino and hydrozyl of chitosan on hydrozyl radical scavenging activity

摘要：

In order to determine the effect of the amido and hydroxyl of chitosan on antioxidant activity, a series of Ndeacetylated chitosan with a degree of deacetylation (D.D.) ranging from 45％ to 95％ were prepared using region selective N-acetylation of chitosan. Their carboxymethyl derivatives (CMC) were also synthesized according to previous method. The antioxidant activity was evaluated on the basis of their abilities to scavenge hydroxyl radical. The results indicated that the hydroxyl radical scavenging ability depended on the degree of deacetylation and concentration. It also showed that the 2-NH2 had a closer relation than 6-OH in hydroxyl radical scavenging activities.

关键词： degree of deacetylation carbozymethyl chitosan hydrozyl radical scavenging

作者: Fang Dong Qinzhao Xue Jingli Liu Hongmao Zhong Huili SUN

作者单位: Yantai Institute of Coastal Zone Research for Sustainable Development,Chinese Academy of Sciences,Ya Yantai Institute of Coastal Zone Research for Sustainable Development,Chinese Academy of Sciences,Ya South China Sea Institute of Oceanology Chinese Academy of Sciences,Guangzhou,China

会议类型: 国际会议

会议名称: The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 1-4

在线出版日期: 2009-06-11（万方平台首次上网日期，不代表论文的发表时间）