Hemodynamic effect of calcifed plaque on blood flow in carotid artery disease: A preliminary study Hemodynamic effect of calcified plaque
The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a sample patient data, with normal and calcified carotid artery appearances. Circular calcified carotid plaque was found at the carotid bifurcation based on 3D computed tomography images. A computational fluid dynamics was performed to analyze the changes of blood flow in different situations. Our results showed that apparent turbulence was found in the diastolic phase at the carotid bifurcation in normal carotid artery geometry. In the presence of the calcified plaque, the flow velocity was increased to some extent, indicating the effect of plaque on hemodynamic changes. Wall shear stress was noticed to decrease at the aortic branches, and this indicates the potential risk of developing stenosis at this area. Our preliminary study demonstrates fluid structure interaction between calcified plaque and artery in terms of flow changes and wall shear stress.
carotid artery disease calcification blood flow computed tomography model
Zhonghua Sun Bibombe Mwipatayi Thanapong Chaichana Curtise Ng
Department of Imaging and Applied Physics Curtin University of Technology Perth,Australia Department of Vascular Surgery Royal Perth Hospital Perth,Australia Department of Electronic Engineering King Mongkuts Institute of Technology Ladkrabang Bangkok,Thail
国际会议
北京
英文
1-4
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）