Effect of Qinglongyi Polysaccharide on Cation Concentration in Erythrocyte of S180 Mice
To study the effect of qinglongyi polysaccharide on cation concentration in erythrocyte of S180 mice A tumor mouse model was developed, and the mice were treated with high, medium, and low doses of qinglongyi polysaccharide through abdominal injection for 7 d. Erythrocytes were collected and erythrocyte suspensions were prepared. Change of Ca2+ concentration in the erythrocytes of S180 mice was measured by stained with Fluo-3/AM and observed with laser scanning confocal microscope, Change of H+ concentrations measured by stained with BCECF-AM and observed with laser scanning confocal microscope. Results showed Qinglongyi polysaccharide lowered the concentration of Ca2+ and H+ in erythrocytes of S180 mice, which is remarkable compared with negative control group(P<0.05). Conclusion Qinglongyi polysaccharide can maintain the stability and balance of cation concentration in erythrocyte of S180 mice.
qinglongyi polysaccharide erythrocyte cation
Yu bin JI Chen feng JI XIANG ZOU
Engineering Research Center of natural antineoplastic drugs,Ministry of Education Center of Research and Development on Life Sciences and Environmental Sciences Harbin University of Commerce Harbin,China
国际会议
北京
英文
1-3
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）