Preparation of Irisquinone Hydrozypropyl-β- Cyclodeztrin Inclusion Complez and its thermodynamic stability

摘要：

The inclusion complex formation of irisquinone with hydroxypropyl-β-cyclodextrin(HP-β-CD) and the physico-chemical properties were studied. Complex of host molecules with irisquinoe was studied by x-ray diffraction (XRD) and differential scanning calorimetry(DSC). The quantitative analysis with uv-vis indicated that HP-β-CD could increase the solubility of irisquinone, where the best results was given with HP-β-CD: irisquinone 2:1 molar ratio. The binding constants of inclusion complex formulation were obtained with relative Higuchi Principle and thermodynamics equation.

关键词： Irisquinone Inclusion complez Identification Apparent solubility

作者: Xue-Nong ZHANG Jin-Hong GONG Li-Hua TANG Qiang ZHANG

作者单位: College of Pharmacy,Soochow University,Suzhou 215123,Peoples Republic of China

会议类型: 国际会议

会议名称: The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 1-4

在线出版日期: 2009-06-11（万方平台首次上网日期，不代表论文的发表时间）