Lipase catalyzed synthesis of ethyl lactate

摘要：

Ethyl lactate was synthesized by lipase catalyzed between lactic acid and ethanol in organic medium for the first time. The experiments showed that the optimal solvent is Tert-buty alcohol and the optimal lipase is Novozym 435. The optimal reaction with a conversion of 77％ can be reached when the molar ratio (acid: alcohol) is 1:8, the temperature is 60℃, the acid concentration is 0.3mol/L, the lipase concentration is 45g/mol, reaction time is 24 hours and the revolutions is 200 rpm. Novozym 435 can be used continuously for six times and a conversion of 60％ can be reached.

关键词： ethyl lactate lipase catalysis esterification

作者: Huang Zhihong Gao Jing Zhao Tiantao

作者单位: School of Chemical Engineering and Technology,Hebei University of Technology,Tianjin 300130,China School of Bioengineering,Chongqing Institute of Technology,Chongqing 400050,China

会议类型: 国际会议

会议名称: The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 1-4

在线出版日期: 2009-06-11（万方平台首次上网日期，不代表论文的发表时间）