Optimization of Solid Phase Eztraction (SPE) for the determination of Synthetic Musks in water by Gas Chromatography-Mass Spectrometry (GC-MS)
A procedure for the determination of synthetic musks compounds (Galaxolide (HHCB), Tonalide (AHTN), musk xylene (MX) and musk ketone (MK)) in water samples was described. Analytes were extracted from the samples using solid phase extraction (SPE) system on ENVI-C18 cartridges and then determined by gas chromatography-mass (GC-MS). Influence of five experimental parameters (volume of eluent, composition ratio of eluent, flow rate during eluted process, methanol content in washed solution and pH of water samples) on the recovery efficiency of the SPE procedure was systematically studied using a U9(95) quasi-level uniform design at three levels. Four mathematical models were obtained from nine experiments. The optimized results were in order of 12 ml, 67％ n-hexane, 0.5 ml/min, 10％ methanol, pH 6.0.Under optimal extraction conditions, recoveries from 72.15％ to 90.46％ were obtained for spiked water samples with relative errors from 0.80％ to 9.21％.
solid phase eztraction (SPE) synthetic musks uniform design (UD) interactive-effect
Wen-jing Sang Xue-fei Zhou Ya-lei Zhang
College of Environmental Science and Engineering Tongji University Shang Hai,China
国际会议
北京
英文
1-4
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）