Hydrogenation of Ketones on Platinum:Origin of Enantioselection
1.Introduction Among the various approaches forwarded in heterogeneous asymmetric catalysis, the simplest and synthetically most attractive method is the addition of a chirai molecule -the modifier -to a (supported)metal catalyst1. There are obvious analogies between a chirally modified metal surface where the strongly adsorbed modifier provides the chiral environment for the transformation of the substrate and a soluble transition metal complex possessing ligands as the source of chiral information. The former system is, however, more complex and structurally less defined. The modifier interacts with not one single metal atom but an ensemble of surface metal atoms. In addition, the metal surface imposes considerable geometric constraint for the modifier-substrate interaction and no truly in situ spectroscopic investigation is yet possible to support a mechanistic concept.
asymmetric hydrogenation ATR-IR spectroscopy theoretical calculations
Tamas Mallat Alfons Balker
Department of Chemistry and Applied Biosciences,ETH Zurich,Honggerberg,CH-8093 Zurich,Switzerland
国际会议
江苏镇江
英文
20-21
2008-10-15（万方平台首次上网日期，不代表论文的发表时间）