Antiozidant Activity of Albumin Binding Salphen Schiff-base Cobalt Complezes

摘要：

1.Introduction Schiff-base metal complexes have been investigated as effective scavengers of ROSs, acting as antioxidants1 However, many Schiff-base metal complexes are insoluble, which limited their application. Serum albumins are the major soluble proteins in the circulatory system. The most outstanding property of albumins is their ability to bind reversibly endogenous and exogenous compounds2. Here, Salphen Schiff base Co complexes was bound into BSA, which afforded water soluble biopolymer supported Salphen Schiff base metal complexes. Their activities for scavenging the free radical were investigated.

关键词： Hydrozyl radicals antiozidants Bovine serum albumin Salphen Schiff-base cobalt complezes

作者: Gang Li Juanjuan Mao Yufeng He Rongmin Wang

作者单位: Key Laboratory of Polymer Materials of Gansu Province,College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070,China

会议类型: 国际会议

会议名称: 18th International Symposium on Fine Chemistry and Functional Polymers,4th IUPAC International Symposium on Novel Materials and Their Synthesis(第18届国际精细化学和功能高分子学术讨论会暨第四届IUPAC 国际新型材料及其制备学术讨论会)

会议地点: 江苏镇江

会议语种:英文

页码: 51-52

在线出版日期: 2008-10-15（万方平台首次上网日期，不代表论文的发表时间）