The Rhodium Catalyzed Carbene Cyclization-Cycloaddition Cascade (CCCC) Reaction of Vinylsulfonates

摘要：

1.Introduction Medium-size rings and cyclic ethers are becoming increasingly recognized as common structural units in naturally occurring compounds, the 1,3-dipolar cycloaddition of carbonyl ylides with π bonds represent an attractive strategy to assemble them.1 Due to the electron-deficiency of the sulfonyl substituted olefin moiety, vinylsulfonates such as 1 are highly reactive substrates for the 1,3-dipolar cycloadditon cyclization reaction. Aiming at the development of novel sultone-based methodology,2 we herein report our detailed studies on the synthesis of tricyclic sultones such as 2 via intramolecular rhodium catalyzed CCCC reaction. 1,3(Scheme 1)

关键词： Rhodium catalyzed Vinylsulfonates Carbene Cyclization Cycloaddition

作者: Bairu Shi Sandra Merten David Wong Pauline Chiu Peter Metz

作者单位: Organische Chemie I,Technische Universit(a)t Dresden,Dresden 01069,Germany Department of Chemistry,The University of Hong Kong,Hong Kong,China

会议类型: 国际会议

会议名称: 18th International Symposium on Fine Chemistry and Functional Polymers,4th IUPAC International Symposium on Novel Materials and Their Synthesis(第18届国际精细化学和功能高分子学术讨论会暨第四届IUPAC 国际新型材料及其制备学术讨论会)

会议地点: 江苏镇江

会议语种:英文

页码: 53-54

在线出版日期: 2008-10-15（万方平台首次上网日期，不代表论文的发表时间）