Iodine as a Catalyst for Conversion of Carbonyl Compounds into Precursors of Antimalarial Perozides

摘要：

1.Introduction In recent years an increasing resistance of malaria parasites to commonly used alkaloidal drugs and the discovery of the antimalarial properties of artemisinin1, has boosted interest in organic peroxides as potential antimalarials2. Dihydroperoxides and perketals are key intermediates in the synthesis of many classes of peroxides, such as tetraoxanes and other tetraoxacycloalkanes, macrocylic endoperoxides and acyclic analogues with a variety of functional groups3. Organic peroxides are also valuable chemicals that serve as radical initiators and oxidants4,5.

关键词： antimalarial perozides dihydroperozide iodine perozyketal hydrogen perozide

作者: Katja (Z)mitek Stojan Stavber Marko Zupan Jernej Iskra

作者单位: Laboratory of Organic and Bioorganic Chemistry,Jo(z)ef Stefan Institute,Jamova 39,Ljubljana,Sloven Faculty of Chemistry and Chemical Technology,University of Ljubljana,A(s)ker(c)eva 5,Ljubljana,Slove

会议类型: 国际会议

会议名称: 18th International Symposium on Fine Chemistry and Functional Polymers,4th IUPAC International Symposium on Novel Materials and Their Synthesis(第18届国际精细化学和功能高分子学术讨论会暨第四届IUPAC 国际新型材料及其制备学术讨论会)

会议地点: 江苏镇江

会议语种:英文

页码: 72-73

在线出版日期: 2008-10-15（万方平台首次上网日期，不代表论文的发表时间）