Study on pH Sensitivity of a Novel Chitosan Derivative Electrodeposition Film by Electrochemical Method
1.Introduction The stimuli-sensitive system thatresponds to the changes of environmental condition such as temperature, pH, chemical species, electrical pulses, etc. Can be effectively applied to many biomedical fields such as drug delivery system and bioseparation process. Therefore, the design of effective stimuli-sensitive system promises the progress in a great many biomedical fields 1. Chitosan (CS) is a copolymer of D-glucosamine and Nacetylglucosamine derived from naturally abundant chitin, which was reported a potentially useful pharmaceutical material owing to its non-toxicity, high biocompatibility and non-antigenicity that offer advantages for possible clinical uses 2, as a pH-sensitive hydrogel, swells under acidic conditions due to protonation of their free amino groups is currently receiving a great deal of interest for medical and pharmaceutical applications that utilize chitosan in various chemical and physical gel forms 3.
monomethozy-poly(ethylene glycol)-grafted-chitosan ph sensitivity electrodeposition
Sheng Yin Kun Wang Qianqian Shi Huaming Li
School of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang 212013,China
国际会议
江苏镇江
英文
327-328
2008-10-15(万方平台首次上网日期,不代表论文的发表时间)