Research of Improved Phylogenetic Profiling Method
(0) In the past few years, great efforts have been made on the improvement of phylogenetic profile method. Most of the researches focused on the selection of reference genome, and so far as we know, no published literature proposed a weight-based phylogenetic profile. In this study, we improved phylogenetic profile method in two aspects: one was to construct weight-based profiles for target proteins; the other was to combine hierarchical cluster method and K-means algorithm to analyze similarity among profiles. Our method make the construction of phylogenetic profile independent on the selection of reference genome, and the results indicated that our refined method performed a better performance.
phylogenetic profile weight-based reference genome hierarchical cluster method K-means algorithm Introduction
Yanan MA Pingping SUN Yuanping Sun Ying Cui Zhiqiang MA
School of Computer, Northeast Normal University Northeast Normal University, NENU ChangChun, 130117 China
国际会议
上海
英文
233-236
2008-05-16（万方平台首次上网日期，不代表论文的发表时间）