The Recognition of Subcellular Localization of Proteins Based on their N-terminal Amino Acid Sequence

摘要：

Functional annotation of unknown proteins is a major goal in proteomics. A key annotation is the prediction of a proteins subcellular localization. We used the method of Increment of Diversity with Quadratic Discriminant analysis (IDQD) to predict subcellular localization of proteins which are recognized by the four plant categories and three non-plant and obtained accuracies at 87.4(±0.5)％ and 91.2(±0.2)％, respectively in 5-fold cross-validation test. Our result is better than other methods currently published.

关键词： subcellular localization Increment of Diversity Quadratic Discriminant analysis amino acid composition Nterminal targeting signal

作者: Jia Yun Zhao Judong Lu Jun

作者单位: Department of physics, Faculty of Science Inner Mongolia University of Technology Hohhot, China

会议类型: 国际会议

会议名称: The 2nd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议)

会议地点: 上海

会议语种:英文

页码: 245-248

在线出版日期: 2008-05-16（万方平台首次上网日期，不代表论文的发表时间）