Similar histone acetylation pattern of neighboring genes in yeast

摘要：

Neighboring genes were found to have a similar expression pattern in eukaryotic genome. But the reason is not clear yet. We find that immediate neighboring genes in yeast show a strong positive correlation in histone acetylation pattern. The co-modification (similar acetylation pattern) extends to neighboring pairs within 12 genes or 11 kbp on chromosomes. These results suggest that chromatin acetylation patterns may play a role in coexpression (similar expression pattern) of neighboring genes.

关键词： coezpression co-modification neighboring genes histone acetylation pattern

作者: Yangyang Deng Xianhua Dai

作者单位: Department of Electronics & Communications Engineering, School of Information Science and Technology Department of Electronics & Communications Engineering, School of Information Science and Technology

会议类型: 国际会议

会议名称: The 2nd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议)

会议地点: 上海

会议语种:英文

页码: 357-360

在线出版日期: 2008-05-16（万方平台首次上网日期，不代表论文的发表时间）