Study on N-Nitrosoureas by Electron Spray Ionization Mass Spectrometry
The mass spectrometric characteristics of Nmethyl-N-nitrosourea (MNU) and N-ethyl-N-nitrosourea (ENU) were investigated by electrospray ion trap mass spectrometry in a multi-stage MS full scan mode. The mass spectra were interpreted according to the fragments of these compounds and their fragmentation patterns were proposed. The results showed that the strong M+H+ ion cluster was obtained in the positive mode when the sample dissolved in acetonitrile. During the process of collision induced dissociation, they underwent the neutral loss of NO and HOCN. These characteristics can be applied further to the elucidation of the fragmentation pathways.
N-methyl-N-nitrosourea N-ethyl-Nnitrosourea electrospray ion mass spectrometer fragmentation pathway
Yuan-Yuan Li Li-Jiao Zhao Shu-Fen Zhang Ru-Gang Zhong
College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100022, China
国际会议
上海
英文
1139-1141
2008-05-16（万方平台首次上网日期，不代表论文的发表时间）