A Novel NMR Simulation Algorithm and Its Potential Application in In Vivo Research
Nuclear Magnetic Resonance (NMR) provides noninvasive detection for molecular information. Recently, intermolecular Multiple Quantum Coherences (iMQCs) was proved to be a promising NMR method to get high-resolution in vivo magnetic resonance spectroscopy (MRS) under inhomogeneous field. The simulation of NMR plays an important role in predicting the result of a complex experiment, developing new NMR experiments, etc. However, in the simulation of iMQC-MRS, there is obstacle of combining scalar couplings with the classic formalism. This paper introduces an iMQC simulation algorithm based on the combination of product operator matrix (POM) and nonlinear Bloch equation, and its applications in developing high-resolution spectroscopy with solvent suppression and region-localized in vivo molecular spectroscopy.
simulation algorithm product operator matriz intermolecular multiple quantum coherence high-resolution magnetic resonance spectroscopy nuclear magnetic resonance
Meijin Lin Chao Fang Congbo Cai Xi Chen Zhong Chen Meijin Lin Zhong Chen
Department of Physics Xiamen University Xiamen 361005, P.R.China Department of Oceanography Key Laboratory of Underwater Acoustic Communication and Marine Informatio
国际会议
上海
英文
2256-2259
2008-05-16（万方平台首次上网日期，不代表论文的发表时间）