Study on Purification of Used Ozygen-18 Water in Preparation of Positron with Cyclotron
A novel method for recovering used O-18 water in 18FFDG synthesis was developed. Base on the properties of anhydrous salt and salt with crystal water, anhydrous potassium fluoride and sodium sulfide were used to accomplish purification of used O-18 water. With the self-assembled instruments, the contaminants of methanol, ethanol and acetonitrile were decreased from 103 ppm, 496 ppm, 571 ppm to less than 32 ppm, 63 ppm, 50 ppm for methanol, ethanol and acetonitrile, respectively. The no-oxygen salt avoided to induce new oxygen-16 contaminants. Recovered O-18 water was used in radiotracer synthesis and gave similar radiochemical yield to new O-18 water.
radiopharmeceuticals O-18 water Positron PET medicine radiotracer nuclear reaction F-18-fluorine
Li-Quan Sun Shingo Kasamatsu Takako Furukawa Yasuhisa Fujibayashi
School of Life Science and Technology Beijing Institute of Technology Haidian District, Beijing, 100 Biomedical Imaging Research Center University of Fukui Eiheiji, Yoshida, Fukui, 910-1193, Japan
国际会议
上海
英文
3504-3506
2008-05-16（万方平台首次上网日期，不代表论文的发表时间）