Effects of Microwaves from GSM Mobile Phones on the Blood-brain Barrier and Neurons in Rat Brain
Our group has since 1988 studied the effects of different intensities and modulations of 915MHz RF in a rat model where the exposure takes place in a TEM-cell during various time periods and post exposure recovery times. The power fed into TEM-cells was 0.125,1.25,12.5 or 125mW corresponding to whole body SAR (determined experimentally): 0.2,2,20 or 200mW/kg. The rats were awake and not restrained during exposure and after the recovery period the animals were anaesthetized and sacrificed by perfusion-fixation with 4％ formaldehyde. Paraffin embedded 5 μm. Thick brain slices were stained for albumin by applying albumin antibodies (Dakopatts),by which albumin is revealed as brownish discolorations. Dark neurons were revealed by staining for RNA/DNA with cresyl violet. In series of more than 1800 Fisher rats,we have proven that sub thermal power levels from both pulsemodulated and continuous RF fields-including those from real GSM mobile phones-have the potency to significantly open the BBB for the animals own albumin (but not fibrinogen) to pass out into the brain and to accumulate in the neurons and glial cells surrounding the capillaries. Albumin extravasations are most prominent at the lower SAR values. This dose-response behaviour suggests some kind of energy or electromagnetic field strength windowing effect. A linear dose-response relationship for dark neurons was found at 50 days after exposure,with most prominent occurrence at SAR 200mW/kg.
Bertil RR Persson Jacob Eberhardt Lars Malmgren Mikael B Persson Arne Brun Leif G Salford
Lund University,Sweden
国际会议
Progress in Electromagnetics Research Symposium 2005(2005年电磁学研究新进展学术研讨会)(PIERS 2005)
杭州
英文
638-641
2005-08-22（万方平台首次上网日期，不代表论文的发表时间）