A NOVEL STRATEGY FOR ANALYZING MIRNA SEQUENCES OF SOLID SYSTEM BASED ON 2-BASE COLOR CODES

摘要：

More and more miRNAs have been identified by the next-generation sequencing platforms. The SOLiD System, which is capable of highest throughput, relative shorter read length and an error-checking mechanism, is appropriate for miRNAs sequencing. Here we implemented an efficient data structure (tries) for analysis of SOLiD miRNAs sequences. The tries offer searches with costs which are independent of the size of sequences being searched. Also the characteristic of miRNAs is suitable for construction of tries. Our experiments show that the data structures of tries not only speedup the procedure of searching, but also save space of memory. Above all, this method based on 2 - base color insures high accuracy.

关键词： miRNAs tries SOLiD 2-base color.

作者: Lu Jiafeng Yang Qi Yu Pinfei Ge Qinyu Lu Zuhong

作者单位: State Key Laboratory of Bioelectronics, Southeast University, China Key Laboratory of Child Development and Learning Science, Southeast University, China State Key Laboratory of Bioelectronics, Southeast University, China Key Laboratory of Child Developm

会议类型: 国际会议

会议名称: The 6th International Forum on Post-genome Technologies(6IFPT)(第六届国际后基因组生命科学技术学术论坛)

会议地点: 北京

会议语种:英文

页码: 60-63

在线出版日期: 2009-09-17（万方平台首次上网日期，不代表论文的发表时间）