SIGLE-AND MULTI-ANALYTE DETERMINATION USING A CHIP-BASED SURFACE ENHANCED RAMAN SCATTERING SYSTEM

摘要：

A portable analysis system, integrating laminar flow chip with surface-enhanced Raman scattering detection has been developed for single- and multi-analyte analysis in blood. A stable mixing of uric acid and silver colloid was achieved by laminar diffusion in a long snakelike microchannel. Quantitative analysis of uric acid was carried out by a portable Raman spectrometer. The detection limit of uric acid was estimated to be 0. 1 μg/mL. In the multi-analyte analysis with this system, uric acid and xanthine were analyzed simultaneously. The chip-based SERS analysis system is proposed to be a portable, sensitive and multianlyte analysis sensor for diagnosis.

关键词： Microfluidic chip Laminar flow Surface-enhanced Raman scattering Multianalyte

作者: Ma Sai Liang Qionglin Wang Yiming Luo Guoan

作者单位: Department of Chemistry,Tsinghua University,Beijing 100084,China

会议类型: 国际会议

会议名称: The 6th International Forum on Post-genome Technologies(6IFPT)(第六届国际后基因组生命科学技术学术论坛)

会议地点: 北京

会议语种:英文

页码: 151-153

在线出版日期: 2009-09-17（万方平台首次上网日期，不代表论文的发表时间）