Effect of Asparagus polysaccharide on the number and activity of erythrocyte complement receptor 1(CD35) of S180 mice
To study the effect of Asparagus officinalis polysaccharide on the number and activity of erythrocyte complement receptor 1(CD35) in S180 mice Red blood cells from mice venous blood are labeled by rat anti-mouse CD35 monoclonal antibody and FITC-conjugated goat anti-mouse antibody. Using flow cytometry, we determined the number of CR1. Using microscope, we studied the adherence between erythrocyte immunity and C3b receptor or tumor-cell by RBC-C3bRR and DTER. Comparing the mean value of the number of CR1 on erythrocyte of high and middle groups with control groups, the mean value of the number of CR1, RBC-C3bRR and DTER of Asparagus officinalis polysaccharide groups are increased significantly. Asparagus officinalis polysaccharide can improve the erythrocyte function of S180 mice, which may be one of antitumor mechanisms.
Yu bin JI Chen feng JI Yong cui MIN
Engineering Research Center of natural antineoplastic drugs, Ministry of Education Center of Research and Development on Life Sciences and Environmental Sciences Harbin University of Commerce Harbin,150076,China
国际会议
2009 IEEE International Symposium on IT in Medicine & Education( IEEE 教育与医药信息化国际会议)
济南
英文
1292-1295
2009-08-14（万方平台首次上网日期，不代表论文的发表时间）