Ezpression profiling of IGFs and IGF receptors in piglets with intrauterine growth restriction

摘要：

In order to test the hypothesis that expression levels of insulin-like growth factor system is altered in piglets with intrauterine growth restriction (IUGR), the present study was conducted to compare the expression levels of IGF-I, IGF-II, IGFR1, IGFR2 and IGFBP5 in m. Longissimus, liver and kidney in 21-day-old IUGR piglets with normal birth weight (NBW) piglets. Our results showed that the expression level of insulin-like growth factor 1 was significantly lower (p < 0.05) in m. Longissimus, liver and kidney of the IUGR piglets compared with the NBW piglets. However, there were no differences in expression levels of IGF2, IGF1R, IGF2R and IGFBP5 in all tissues tested between NBW and IUGR piglets.

关键词： Piglets Intrauterine growth restriction Insulin-like growth factor system

作者: R.J.Chen Y.L.Yin J.Pan Y.L.Gao T.J.Li

作者单位: Key Laboratory for Agro-ecological Processes in Subtropical Region, Institute of SubtropicalAgricult Key Laboratory for Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agricul

会议类型: 国际会议

会议名称: 4th International Symposium on Animal Nutrition,Health and Feed Additive(第四届动物营养、保健与饲料添加剂国际学术研讨会)

会议地点: 广州

会议语种:英文

页码: 238-243

在线出版日期: 2009-07-04（万方平台首次上网日期，不代表论文的发表时间）