Stem Cells and Breast Cancer
The concept that cancer may be a stem cell disease, arising from tissue stem/progenitor cells or driven by cells with stem cell properties, has important implications for understanding the basic biology of tumorigenesis and is crucially relevant to cancer management, for the development of new strategies for prevention, staging/prognosis and therapy. There is accumulating evidence that breast cancer may arise from mutated mammary stem/ progenitor cells which have been termed breast cancer stem cells or initiating cells because of their exclusive ability to sustain tumor formation and growth.
Maria Grazia Daidone
Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
国际会议
上海
英文
52-53
2008-10-01（万方平台首次上网日期，不代表论文的发表时间）