Evolutionary and genomic analyses of cee, a novel but ancient gene involved in development

摘要：

BackgroundUnlike mammals, teleost fish have the ability to increase their number of fast muscle fibres throughout juvenile and adult stages, until they reach a predetermined body size 1.Since the molecular basis of this phenomenon is poorly understood, we have recently performed a suppression subtractive hybridisation screen to identify novel genes associated with the inhibition of myotube production in the fast myotomal muscle of the model pufferfish (Takifugu rubripes). One of these genes turned out to be particularly interesting, as it was specifically upregulated in fast muscle of fish that had stopped recruiting muscle fibres2. This gene, originally termed FRC386, was subsequently re-named as cee, for conserved edge expressed protein.

作者: Jorge MO Fernandes Daniel J Macqueen Hung-Tai Lee Ian A Johnston

作者单位: Faculty of Biosciences and Aquaculture, Bodo University College, NO-8049 Bode, Norway School of Biology, University of St Andrews, St Andrews, Fife KY16 8LB, UK

会议类型: 国际会议

会议名称: The 7th Asia-Pacific Bioinformatics Conference(第七届亚太生物信息学大会)

会议地点: 北京

会议语种:英文

页码: 823

在线出版日期: 2009-01-01（万方平台首次上网日期，不代表论文的发表时间）