Identifying Conserved Regions for Protein Structure Prediction

摘要：

BackgroundThreading is one of the most effective strategies for protein structure prediction. We observe from CASP7 that for a given target sequence, threading methods usually generate many structures that are partially similar to the native structure. This observation inspires us that a threading decoy can be partitioned into conserved regions and non-conserved regions. Identifying conserved regions from multiple decoys is important to improve structure prediction. The subject of this paper is two-fold:designing efficient methods to identify conserved regions, and then applying these conserved regions to improve protein structure prediction.

作者: Yi Wei Jishuang Yang Dongbo Bu

作者单位: Bioinformatics Group, Institute of Computing Technology, Chinese Academy of Sciences, China

会议类型: 国际会议

会议名称: The 7th Asia-Pacific Bioinformatics Conference(第七届亚太生物信息学大会)

会议地点: 北京

会议语种:英文

页码: 867

在线出版日期: 2009-01-01（万方平台首次上网日期，不代表论文的发表时间）