Improved computational prediction of prokaryotic protein subcellular localization

摘要：

BackgroundComputational prediction of protein subcellular localization for bacteria has reached a level of precision comparable to certain highthroughput experimental determination techniques. The Brinkman lab has previously developed PSORTb, capable of assigning a query bacteria protein to one of four Gram-positive or five Gram-negative localization sites with a measured overall precision of 97%; however,due to its lower recall, it only makes predictions for approximately 50% of proteins encoded in typical Gram-negative bacterial genomes and 75% of those in Gram-positive bacterial genomes.

作者: Nancy Yu James Wagner Matthew Laird Raymond Lo Martin Fster Fiona Brinkman

作者单位: Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada Department of Computer Science, Simon Fraser University, Burnaby, Canada

会议类型: 国际会议

会议名称: The 7th Asia-Pacific Bioinformatics Conference(第七届亚太生物信息学大会)

会议地点: 北京

会议语种:英文

页码: 873

在线出版日期: 2009-01-01（万方平台首次上网日期，不代表论文的发表时间）