IC for Neural Signal Regeneration
Based on the 4-channels neural signal regeneration system which was realized by using discrete devices and successfully used for in-vivo experiments of rats and rabbits,an integrated circuit (IC) with 6-channels of neural signal regeneration has been designed and realized in CSMCs 0.6μm CMOS technology. The IC consists of a neural signal amplifier with adjustable gain,a buffer stage,and a function electrical stimulation (FES) stage. The neural signal detecting circuit amplifies the detected weak signal come from the electrode to such a voltage that the FES circuit can be driven appropriately. The FES circuit amplifies the signal further so that the neural signal can be regenerated through the stimulating electrode. The neural signal regenerating IC occupies a die area of 2.82mm×2.00mm. Under double supply voltages of ±2.5V,the DC power consumption is less than 50 mW. The on-wafer measurement results are as follows: the output resistor is 118 mΩ,the 3dB bandwidth is greater than 30 kHz,and the gain can be variable from 50dB to 90dB. The circuit has been used for in-vivo experiments on the rats sciatic nerve as well as spinal cord with the cuff type electrode array or a needle twin-electrode,and the neural signal has been regenerated successfully both on a rats sciatic nerve bundle and on a spinal cord.
Neural Signal egeneration FES IC CMOS
LI Wenyuan WANG Zhigong
Institute of RF-& OE-ICs.Southsast University,Nanjing,Jiangsu,210096 Institute of RF-& OE-ICs,Southeast University,Nanjing,Jiangsu,210096
国际会议
9th International Conference on Solid-State and Integrated-Circuit Technology(第9届固态和集成电路国际会议)
北京
英文
1749-1752
2008-10-20（万方平台首次上网日期，不代表论文的发表时间）