Stereochemistry on the Formation of Syringylglycerol-8-O-4-(Sinapyl Alcohol) Ether from Sinapyl Alcohol with Enzyme Preparations of Eucommia ulmoides
Introduction Lignans and neolignans are dimeric phenylpropanoides and widely distributed in higher plants. Most of them are optically active. They have important physiological functions in plant defense and human health. Recently, its have been reported that Surinamensin (8-0-4 neolignan) has potential anti-leishmanial activity. In contrast to lignans, biosynthesis of 8-0-4 neolignans has not been advanced. However, Katayama and Kado found for the first time that incubation of cell-free extracts from Eucommia ulmoides with coniferyl alcohol (CA) in the presence of H2O2 gave (+)-erythro-and (-)-threo-guaiacylglycerol-8-O-4-(coniferyl alcohol) ether (GGCE) and that the erythro isomer was preferred to the threo one. Very recently Lourith et al.1 found the stereoselective formation of erythro-GGSE and erythro-syringylglycerol-8-O-4-(sinapyl alcohol) ether (SGSE) with optical activity by feeding experiments, in this study, to clarify stereochemistry on the formation of SGSE from sinapyl alcohol (SA) in E. ulmoides, enzyme reactions were carded out.
Shameul Alam Takeshi Katayama Toshisada Suzuki
Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kagawa 761-0795, Japan
国际会议
International Symposium on Wood Science and Technology(IAWPS 2008)(国际木材产品学会联合会2008学术研讨会)
哈尔滨
英文
339-340
2008-09-27（万方平台首次上网日期，不代表论文的发表时间）