Effects of electromagnetic pulse on the tight junction of mice blood-testis-barrier
AIM To investigate the changes of the mice testes and the tight junction (Tj) relative molecular and to identify the molecular mechanisms of the mice blood-testis-barrier BTB permea-bility increasing after the mice were exposed to electromagnetic pulse (EMP).METHODS Observe the changes vimentin of the mice testes by laser scanning confocal technique.RESULTS After the 200kVm-1 EMP (the accumulative pulse times was 200) exposure,the vimentin in sustentacular cells of testis became irregularly shortened and derangement,and the intensity of immuno-fluorescence also showed ununiformity compared with control.CONCLUSION The increasing of mice BTB permeability perhaps caused by the changing of vimentin.
Wang Xiao-Wu Guo Guo-Zhen Ding Gui-Rong Zeng Li-Hua Liu Xiao-Wei Miao Xia Zhao Tao Zhang Jie Xie Xue-Jun Su Xiao-Ming
Department of Radiation Medicine,Faculty of Preventive Medicine,Fourth Military Medical University,X Department of Nephrology,Xijing Hospital,Fourth Military Medical University,Xian 710033 China
国际会议
昆明
英文
2008-11-01（万方平台首次上网日期，不代表论文的发表时间）