Atomic Force Microscope Observation on CHO Cell Membrane after Electromagnetic Pulses Irradiation
Atomic force microscope (AFM) has been used to visualize the morphological change on the surface of CHO cell membrane before and after Electromagnetic pulses (EMP)irradiation.The results showed that there were different sizes and shapes of membrane perforate (the width is 0.66-0.39um,the depth is 392.95nm) after 400kV/m 200 pulses EMP irradiation.The numbers of cell membrane perforates were decreased with EMP field intensity and the pulses numbers decreasing.It is suggested that EMP irradiation can cause the membrane perforate of CHO cell directly.The numbers of cell membrane perforates were increased with EMP field intensity and the pulses numbers increasing.EMP induced membrane perforate may play a very important role in EMP bio-effects.
electromagnetic pulse (EMP) Atomic force microscope CHO cell cell membrane
ZENG Li-Hua LI Yuan MIAO Xia WANG Xiao-Wu LANG Hai-Yang ZHANG Jie LI Yu-Rong
Department of Radiation Medicine Faculty of Preventive Medicine,Fourth Military Medical University Hospital of 66069 Army Force,Baoding 071051,China; Department of Radiation Medicine Faculty of Preventive Medicine,Fourth Military Medical University X
国际会议
昆明
英文
2008-11-01(万方平台首次上网日期,不代表论文的发表时间)