Effects of EMP on Bone Formation of MC3T3-E1 Cells

摘要：

The purpose of this study was to investigate the effects of electromagnetic pulse (EMP) on bone formation of MC3T3-E1 cells.Proliferation,ALP activity and mineralized nodule formation were examined in MC3T3-E1 cells after EMP exposure (field intensities: 0kV/m,50kV/m,400kV/m,400 pulses once a day for 7 days).After 50 kV/m EMP exposure,all the parameters of MC3T3-E1 cells were not changed significantly.However,the proliferation,ALP activity and mineralized nodule formation of MC3T3-E1 cells in 400 kV/m EMP exposure groups were decreased.In conclusion,the EMP we used was a possibly harmful factor for bone formation.It may suppress bone formation of MC3T3-E1 cells with higher electric field intensity.

关键词： EMP MC3T3-E1 Proliferation ALP Mineralized nodule

作者: Kangchu Li Shirong Ma Guirong Ding Yongchun Zhou Xiaowu Wang Lihua Zeng Yongbin Chen

作者单位: Department of Radiation Medicine,Fourth Military Medical University,17＃ Changle West Road,Xian,Chin Department of Pathology,Fourth Military Medical University,17＃ Changle West Road,Xian,China 710032

会议类型: 国际会议

会议名称: 第八届电磁理论、天线及传播国际研讨会

会议地点: 昆明

会议语种:英文

在线出版日期: 2008-11-01（万方平台首次上网日期，不代表论文的发表时间）