DEVELOPMENT AND OPTIMIZATION OF A QUANTLTATIVE WESTERN BLOT AND DOT BLOT PROCEDURE FOR THE DETERMINATION OF RESIDUAL HOST CELL PROTEINS PRESENT IN INACTIVATED POLIO VACCINE USING A GZ11 BASED SIGNAL REAGENT

摘要：

INTRODUCTIONInactivated polio vaccine(IPV) contains as the active ingredient protective D-antigens.Because the polio virus is Rrown on a host cell system,residual host cell proteins (HCPs) may be present in the bulk product.During poliovirus cultivation the Vere host cells lyse.

作者: G ZOMER M HAMZINK A DE HAAN G KERSTEN K REUBSAET

作者单位: Unit Research and Development,Netherlands Vaccine Institute,PO Box 457,3720AL Bilthoven,The Netherlands

会议类型: 国际会议

会议名称: The 15th International Symposium on Bioluminescence and Chemilminescence(第十五届生物发光和化学发光国际会议)

会议地点: 上海

会议语种:英文

页码: 287-290

在线出版日期: 2008-05-13（万方平台首次上网日期，不代表论文的发表时间）