DEVELOPMENT OF A NOVEL BIOLUMINESCENT ASSAY FOR NITRIC OXIDE BY USING SOLUBLE GUANYLATE CYCLASE

摘要：

INTRODUCTIONNitric Oxide(NO) has been known to be involved in many biological processes including vasodilatation and neuronal communjcation.Soluble guanylate cyclase (sGC),which is a well-knownNO-sensor,plays an essential role in signal transduction with respect to enzyme initiation for the conversion of GTP to cGMP in the NO signaling cascade,leading to the concomitant production of pyrophosphate(PPi).

作者: YOSHIHIRO SANO MASAYUKI SEKI SHIGEYA SUZUKI SEIJI ABE KATSUTOSHI ITO HIDETOSHI ARAKAWA

作者单位: School of Pharmaceutical science,Showa University,Tokyo 142-8555.Japan Research ＆ Development Division,Kikkoman Corporation,Chiba 278-0037.Japan

会议类型: 国际会议

会议名称: The 15th International Symposium on Bioluminescence and Chemilminescence(第十五届生物发光和化学发光国际会议)

会议地点: 上海

会议语种:英文

页码: 109-112

在线出版日期: 2008-05-13（万方平台首次上网日期，不代表论文的发表时间）