DYNAMICS OF THE CYTOSKELETON: A PORTRAIT OF LIVING CELLS AS HETEROGENEOUS AND NONEQUILIBRIAL ATERIALS

摘要：

Dynamics of cytoskeleton (CSK) largely determines the living cells mechanicalproperties that are important for cell functions both in health and disease.Despiteextensive studies,CSK dynamics is still not fully understood due in part to itscomplex and heterogeneous nature.Here,we present our recent studies on thecomplex modulus of CSK with respect to strain frequency.We demonstrate thatliving cells are not only heterogeneous,but also in many ways resemblenonequilibrial physical systems,thus suggesting a novel physical portrait of theliving cell as a heterogeneous and nonequilibrial material.

关键词： cytoskeleton living cell heterogeneity complex modulus optical magnetic twisting cytometry

作者: L.H.Deng

作者单位: National 985 Project Institute of Biorheology,and Bioengineering College,hongqing University,Chongqing,Chonqqing,400044,China Program of Molecular and Integrative Physiological Sciences,Harvard School of PublicHealth,Boston,MA,02115,USA

会议类型: 国际会议

会议名称: 第二届国际非均质材料力学会议(The Second International Conference on Heterogeneous Material Mechanics)

会议地点: 安徽黄山

会议语种:英文

页码: 582-587

在线出版日期: 2008-06-03（万方平台首次上网日期，不代表论文的发表时间）