Application of Phosphorescence Quenching Technique to In Vivo Microvascular Oxygen Measurements

摘要：

To clarify the oxygen transport across the microvessel and oxygen distribution in the skeletal muscle,we have newly designed an intravital laser microscopy with oxygen-dependent quenching of phosphorescence technique.This microscope was applied to measure the intra-and peri-vascular partial oxygen pressure (pO2) in rat cremaster muscle.A significant drop in pO2 along the arterioles and a large pO2gradient at the blood/tissue interface of arterioles were found.These findings suggest that oxygen is suppliedfrom arterioles to surrounding tissues and arteriolar wall O2 consumption would be high.

作者: M.Shibata A.Kawarada

作者单位: Department of Biomedical Engineering,Graduate School of Medicine,University of Tokyo,Tokyo,Japan Hiroshima prefectural University,Mihara,Japan

会议类型: 国际会议

会议名称: 2008国际生物生理工程研讨会(The International Symposium on Biological and Physiological Engineering/The 22nd SICE Symposium on Biological and Physiological Engineering)

会议地点: 哈尔滨

会议语种:英文

页码: 46-47

在线出版日期: 2008-01-13（万方平台首次上网日期，不代表论文的发表时间）