Packed-Fiber Solid Phase Extraction for Determination of Retinoids as Novel Neurosignaling Molecules in Human Plasma

摘要：

In this study,a novel simple and rapid packed-fiber solid phase extraction(PFSPE)procedure based on electrospun nanofibers for simultaneous determination of retinoids(retinol and retinyl esters)in human plasma has been developed and validated.Parameters affecting extraction efficiency were investigated in detail.PFSPE could significantly simplify the traditional LLE and SPE process for cutting extraction time,in turn improve the sensitivity and reproducibility.It is believed that the assays described here would be great helpful to elucidating retinoids metabolism mechanism and other function with accurate data.

作者: Zhiyong Liu Xuejun Kang Yuqin Ma Jing Sun Zhongze Gu Zuhong Lu

作者单位: School of Public Health,Southeast University,Nanjing 210009,China Key Laboratory of Child Development and Learning Science,Ministry of Education,Research Center For L State Key Laboratory of Bioelectronics,Southeast University,Nanjing 210096,China Key Laboratory of Child Development and Learning Science,Ministry of Education,Research Center For L

会议类型: 国际会议

会议名称: 2008亚太心智、脑和教育学术会议(Asia-Pacific Conference on Mind Brain and Education 2008)

会议地点: 南京

会议语种:英文

页码: 314-317

在线出版日期: 2008-10-25（万方平台首次上网日期，不代表论文的发表时间）