Quantitative Research on Analgesic Effects of Electroacupuncture at Multiple Factors Parameters in Rats of Adjuvant-Induced Arthritis
Objective To research into the best parameters plan of electroacupuncture for treating pain in rats of adjuvant-induced arthritis (AA).Methods One hundred and twenty Wistar rats were randomly divided into 12 groups.Rats of AA arthritis were treated by electroacupuncture at different frequencies,waveforms and current.The analgesia effects of these groups were compared by orthogonal experiment and so on.Pain threshold and the contents of β-EP in local tissues of inflammation were observed.Parameters of electroacupuncture were measured.Results Optimized parameters plan of raising pain thresholds was:100Hz,0.1mA,intermittent wave.Electroacupuncture at 100Hz was prior to that at 2 Hz in increasing the contents of β-EP.Difference of analgesic effects of electroacupuncture between 4/20Hz,0.1mA,dense-disperse wave and 100Hz,0.1mA,intermittent wave on inflammatory pain in rats had no statistics significance (P>0.05).Conclusions Optimized parameters plan of electroacupuncture should be selected in treating pain in rats of AA.Quantization and standardization of electroacupunture should be further enhanced.
E1ectroacupuncture Stimulating Parameters/acup eff Acupuncture Analgesia
Le Kuai Huayuan Yang, Jie Jiang
Lab of TCM Engineering,College of Acupuncture-Moxibustion and Tuina,Shanghai University of TCM,Shanghai 201203,China
国际会议
7th Asian-Pacific Conference on Medical and Biological Engineering(第七届亚太地区生物工程学术会议)
北京
英文
2008-04-22（万方平台首次上网日期，不代表论文的发表时间）