A Novel Taste Sensor Based on Ion Channels Incorporated in Nano-lipid Bilayer Membranes

摘要：

Biological studies have elucidated the gustatory detection of taste receptor cells often take place on ion channels or receptors in cells membranes.In this study,we build a novel electronic tongue based on ion channels of channel-active peptides gramicidin incorporated in lipid bilayer membranes with highly ordered nanopores.By impedance analysis,this novel biomimetic sensing systems can separate tastants by their functional characters to ion channels.This nano-lipid platform is useful to study special ion channels or receptors with potential detecting for special kind of taste.

关键词： Taste sensor Electronic tongue Ion channel Nanopores Lipid bilayer Membranes

作者: Qingjun Liu Jinjiang Yu Zongbin Liu Wei Zhang Ping Wang Mo Yang

作者单位: Biosensor National Special Laboratory,Department of Biomedical Engineering,Zhejiang University,Hangz Department of Health Technology and Informatics,The Hong Kong Polytechnic University,Kowloon,Hong Ko

会议类型: 国际会议

会议名称: 7th Asian-Pacific Conference on Medical and Biological Engineering(第七届亚太地区生物工程学术会议)

会议地点: 北京

会议语种:英文

在线出版日期: 2008-04-22（万方平台首次上网日期，不代表论文的发表时间）