Deformation-Based Morphometric study on Blind mens brain structures
Many studies have shown the functional relevance of cross-modal plasticity in blind men.However,few researches have focused on whether such functional plasticity is associated with macroscopic changes of structural anatomy in brain regions.Fortunately,deformation based morphometry (DBM) provides an important tool for the computational anatomy research.In this study we detected the changes of regional volume in brain structures between the blind men and normal controls with DBM method.Information of the difference is derived from the deformation field acquired during HAMMER non-rigid registration.The experimental results show that the regions expanded in the blind men’s brain are located at Brodmann 19,31 while the contracted regions located at Brodmann 17,18.This research is very helpful to discover the relationship between structural anatomy and functional data of blind men at a macroscopic level from neuroimaging perspective.
deformation based morphometry blind men non-rigid registration
Chunlan Yang Shuicai Wu Yanping Bai Hongjian Gao
College of life science & Bioengineering,Beijing University of Technology,Beijing,China
国际会议
7th Asian-Pacific Conference on Medical and Biological Engineering(第七届亚太地区生物工程学术会议)
北京
英文
2008-04-22（万方平台首次上网日期，不代表论文的发表时间）