Optimization of Anastomotic Configuration in CABG Surgery

摘要：

The geometric factors have prominent impacts on the success rate of coronary artery bypass graft (CABG).In order to clarify how to choose suitable graft-host diameter ratio and junction angle,ANSYS9.0 was used to simulate CABG,then response surface methodology was applied to construct mathematical model,finally theory of optimization was performed to determine the optimum graft-host diameter ratio and junction angle which could make the main factor influencing the success rate of CABG,i.e.wall shear stress gradients,smallest.The result indicates that the model of large graft-host diameter ratio and small junction angle has better hemodynamics.It can be concluded that adopting large grafthost diameter ratio and small junction angle with the help of clinical experiences is advisable in CABG surgery.

关键词： Hemodynamics CABG Optimization Response surface methodology Numerical simulation

作者: Y.Sui B.Ma A.Qiao

作者单位: College of Mechanical Engineering & Applied Electronics Technology,Beijing University of Technology, College of Life Science & Bioengineering,Beijing University of Technology,Beijing,100022,P.R.China

会议类型: 国际会议

会议名称: 7th Asian-Pacific Conference on Medical and Biological Engineering(第七届亚太地区生物工程学术会议)

会议地点: 北京

会议语种:英文

在线出版日期: 2008-04-22（万方平台首次上网日期，不代表论文的发表时间）