Optimizing Process Parameter for Electrospinning Zein Nanofibers Using Response Surface Methodology
(0) The electrospinning of zein was performed with acetic acid,and the morphology of the zein fibers were investigated by scanning electron microscopy (SEM).Box-Behnken experimental design was employed with three main influential parameters,i.e.concentration,electric field intensity and flow rate,as the independent variables and the diameter of the zein fibers as the investigative object.The regression modeling was set up by regression analysis.The results indicate that,the concentration has the most significant influence on the diameter of the fibers,and the next is the interaction item of the electric field intensity and flow rate;the observed responses are in close agreement with the predicted values of the mathematic model.By using of Response Surface Design,the process of experiment at design was simplified and the condition of the desired fiber diameter could be obtained easily according to the mathematic model.This has a great significance to produce nanofibers via electrospinning.
Electrospinning Zein Response surface methodology Box-Behnken design
Yeping Song Jie Xiong Junjun Xie Pengfei Huo Yongpan Wang Fang Sun
Key Laboratory of Advanced Textile Materials and Manufacturing Technology (ZhejiangSci-Tech Universi Clinical Medical College,Hangzhou Normal University,Hangzhou 310036 China
国际会议
杭州
英文
2008-10-15（万方平台首次上网日期，不代表论文的发表时间）