Investigation of multifunctional cell physiological analysis instrument based on integrated chip
This paper describes a novel multifunctional cell physiological analysis instrument based on integrated chip.And we introduces a novel cell sensors chip which integrated MEA,ECIS and light addressable potentiometer sensors (LAPS) which is designed for the purpose of detecting the cell physiological parameters.The instrument has been integrated with a multi-channel high precision open circuit potential measurement system for micro electrode array as well as a potentiostat in ECIS.And an analog lock-in amplifier is also presented to measure the response of LAPS.In addition,in order to achieve multiple analysis,we first tested every parameters of the chip,then we raise different cells on the surface of the chip.The result shows that such biosensors have numerous applications including pharmaceutical screening,cellular physiological analysis,toxin detecting,peripheral nerve regeneration and environment monitoring.
Multifunctional Instrument Cell Physiological Analysis Integrated Chip Microphysiometer MEA ECIS
Hua Cai Shi Zhu Hui Yu Lidan Xiao Zhaoying Hu Wei Zhang, Ping Wang
Biosensor National Special Laboratory,Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Zhejiang University,Hangzhou,310027,China
国际会议
7th Asian-Pacific Conference on Medical and Biological Engineering(第七届亚太地区生物工程学术会议)
北京
英文
2008-04-22（万方平台首次上网日期，不代表论文的发表时间）